Review



gsmtx 4  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 97
      Buy from Supplier

    Structured Review

    MedChemExpress gsmtx 4
    Typical calcium signature triggered by the addition of 10 µM Srf in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.
    Gsmtx 4, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 108 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gsmtx+4/GsMTx4/pmc13197228-255-16-19
    Average 97 stars, based on 108 article reviews
    gsmtx 4 - by Bioz Stars, 2026-09
    97/100 stars

    Images

    1) Product Images from "Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis"

    Article Title: Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis

    Journal: Nature Plants

    doi: 10.1038/s41477-026-02270-3

    Typical calcium signature triggered by the addition of 10 µM Srf in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.
    Figure Legend Snippet: Typical calcium signature triggered by the addition of 10 µM Srf in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.

    Techniques Used:

    Typical calcium signature triggered by the addition of MAMPs (150 mg ml −1 CO8) in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.
    Figure Legend Snippet: Typical calcium signature triggered by the addition of MAMPs (150 mg ml −1 CO8) in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.

    Techniques Used:

    a , [Ca 2+ ] cyt levels in Col-0 AEQ protoplasts upon Srf (10 µM) or mock (WI Ca ), with or without pre-incubation with the mechanosensitive channel blocker GsMTX-4 (+Gx). n = 20 from four independent experiments. b , [Ca 2+ ] cyt response measured with the Fluo4-AM probe in Col-0 protoplasts treated with Srf (10 µM) or mock (WI Ca ), with or without pre-incubation with GsMTX-4 ( + Gx). Mean ± s.d., data are from four independent experiments with total n indicated. c , [ROS] intra accumulation in Col-0 roots 30 min after Srf (10 µM) or mock (water) treatment, in presence or absence of GsMTX-4 ( + Gx). Data are expressed as fold increase in DCFH-DA fluorescence compared to mock. Mean ± s.d., data are from three independent experiments with total n indicated. d , [Ca 2+ ] cyt signal in Col-0 AEQ protoplasts following Srf (10 µM) or mock (WI Ca ) treatment with or without pre-incubation with the calcium channel blocker LaCl 3 ( + La). Data are from four independent experiments with total n indicated. e , Calcium influx in Col-0 protoplasts measured via Fluo4-AM fluorescence after Srf (10 µM) or mock (WI Ca ) treatment, with or without LaCl 3 pre-treatment. Data are normalized fluorescence increases. Mean ± s.d., data are from at least two independent experiments with total n indicated. f , [Ca 2+ ] cyt signal in UBQ10::GCaMP3 roots treated with Srf (10 µM) or flg22 (1 µM) as MAMP, with ( + La) or without LaCl 3 pre-treatment. Signal quantified as fluorescence increase. Mean ± s.d., total n indicated. P -values from unpaired two-tailed t-test with Welch’s correction. In a and d , data show the average of luminescence (L/L max ) between 1.5 and 4 min post-treatment with Srf. Box plots show medians, quartiles, and ranges. Letters represent statistically different groups ( P < 0.05, two-way ANOVA with Bonferroni’s post-test). In b , c and e , letters indicate statistically different groups at P < 0.05, two-way ANOVA with Tukey’s post-test.
    Figure Legend Snippet: a , [Ca 2+ ] cyt levels in Col-0 AEQ protoplasts upon Srf (10 µM) or mock (WI Ca ), with or without pre-incubation with the mechanosensitive channel blocker GsMTX-4 (+Gx). n = 20 from four independent experiments. b , [Ca 2+ ] cyt response measured with the Fluo4-AM probe in Col-0 protoplasts treated with Srf (10 µM) or mock (WI Ca ), with or without pre-incubation with GsMTX-4 ( + Gx). Mean ± s.d., data are from four independent experiments with total n indicated. c , [ROS] intra accumulation in Col-0 roots 30 min after Srf (10 µM) or mock (water) treatment, in presence or absence of GsMTX-4 ( + Gx). Data are expressed as fold increase in DCFH-DA fluorescence compared to mock. Mean ± s.d., data are from three independent experiments with total n indicated. d , [Ca 2+ ] cyt signal in Col-0 AEQ protoplasts following Srf (10 µM) or mock (WI Ca ) treatment with or without pre-incubation with the calcium channel blocker LaCl 3 ( + La). Data are from four independent experiments with total n indicated. e , Calcium influx in Col-0 protoplasts measured via Fluo4-AM fluorescence after Srf (10 µM) or mock (WI Ca ) treatment, with or without LaCl 3 pre-treatment. Data are normalized fluorescence increases. Mean ± s.d., data are from at least two independent experiments with total n indicated. f , [Ca 2+ ] cyt signal in UBQ10::GCaMP3 roots treated with Srf (10 µM) or flg22 (1 µM) as MAMP, with ( + La) or without LaCl 3 pre-treatment. Signal quantified as fluorescence increase. Mean ± s.d., total n indicated. P -values from unpaired two-tailed t-test with Welch’s correction. In a and d , data show the average of luminescence (L/L max ) between 1.5 and 4 min post-treatment with Srf. Box plots show medians, quartiles, and ranges. Letters represent statistically different groups ( P < 0.05, two-way ANOVA with Bonferroni’s post-test). In b , c and e , letters indicate statistically different groups at P < 0.05, two-way ANOVA with Tukey’s post-test.

    Techniques Used: Incubation, Fluorescence, Two Tailed Test

    Related Articles

    Saline:

    Article Title: GsMTx‐4 inhibits the exercise pressor reflex and the muscle mechanoreflex primarily through TRPC inhibition
    Article Snippet: .. GsMTx-4 (1mg;MedChemExpress) and SAR7334 hydrochloride (5mg;MedChemExpress) were dissolved in 0.9% saline. ..

    Article Title: GsMTx‐4 inhibits the exercise pressor reflex and the muscle mechanoreflex primarily through TRPC inhibition
    Article Snippet: .. GsMTx‐4 (1 mg; MedChemExpress) and SAR7334 hydrochloride (5 mg; MedChemExpress) were dissolved in 0.9% saline. ..

    other:

    Article Title: Lipid asymmetry disruption by XKR8 orchestrates neutrophil extracellular trap formation and inhibits fungal infection
    Article Snippet: Additional inhibitors, including S62845 (HY-100741), emricasan (HY-10396), 2-APB (B6643), SKF96365 (HY-100001), HC067047 (HY-100208), Pyr3 (HY-108465), JNJ-28583113 (HY-149143), 9-phenanthrol (HY-108457), carvacrol (HY-N0711), GsMTx-4 (HY-P1410), probenecid (HY-B0545), GSK1016790A (HY-19608), GSK1702934A (HY-111098), bilirubin (HY-N0323), Yoda1 (HY-18723) and NTB (HY-101302) were obtained from MedChemExpress.

    Article Title: Lipid asymmetry disruption by XKR8 orchestrates neutrophil extracellular trap formation and inhibits fungal infection.
    Article Snippet: Additional inhibitors, including S62845 (HY-100741), emricasan (HY-10396), 2-APB (B6643), SKF96365 (HY-100001), HC067047 (HY-100208), Pyr3 (HY-108465), JNJ-28583113 (HY-149143), 9-phenanthrol (HY108457), carvacrol (HY-N0711), GsMTx-4 (HY-P1410), probenecid (HY-B0545), GSK1016790A (HY-19608), GSK1702934A (HY-111098), bilirubin (HY-N0323), Yoda1 (HY-18723) and NTB (HY-101302) were obtained from MedChemExpress.




    Similar Products

    gsmtx4  (Alomone Labs)
    95
    Alomone Labs gsmtx4
    Gsmtx4, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gsmtx+4/GsMTx-4/10__3390_slash_ijms27052115-133-14-18
    Average 95 stars, based on 1 article reviews
    gsmtx4 - by Bioz Stars, 2026-09
    95/100 stars
    		  Buy from Supplier
    gsmtx 4  (MedChemExpress)
    97
    MedChemExpress gsmtx 4
    Typical calcium signature triggered by the addition of 10 µM Srf in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.
    Gsmtx 4, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gsmtx+4/GsMTx4/pmc13197228-255-16-19
    Average 97 stars, based on 1 article reviews
    gsmtx 4 - by Bioz Stars, 2026-09
    97/100 stars
    		  Buy from Supplier
    tarantula toxin gsmtx4  (Alomone Labs)
    95
    Alomone Labs tarantula toxin gsmtx4
    Typical calcium signature triggered by the addition of 10 µM Srf in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.
    Tarantula Toxin Gsmtx4, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gsmtx+4/GsMTx-4/pm41663229-319-13-29
    Average 95 stars, based on 1 article reviews
    tarantula toxin gsmtx4 - by Bioz Stars, 2026-09
    95/100 stars
    		  Buy from Supplier
    hl3 1 buffer  (Alomone Labs)
    95
    Alomone Labs hl3 1 buffer
    Typical calcium signature triggered by the addition of 10 µM Srf in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.
    Hl3 1 Buffer, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gsmtx+4/GsMTx-4/pm41663229-319-24-29
    Average 95 stars, based on 1 article reviews
    hl3 1 buffer - by Bioz Stars, 2026-09
    95/100 stars
    		  Buy from Supplier

    Image Search Results


    Typical calcium signature triggered by the addition of 10 µM Srf in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.

    Journal: Nature Plants

    Article Title: Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis

    doi: 10.1038/s41477-026-02270-3

    Figure Lengend Snippet: Typical calcium signature triggered by the addition of 10 µM Srf in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.

    Article Snippet: Experiments with the channel blockers included an additional step where LaCl 3 (10 mM; Sigma-Aldrich) or GsMTX-4 (7.5 μM; MedChemExpress) was added 15 min before treatments.

    Techniques:

    Typical calcium signature triggered by the addition of MAMPs (150 mg ml −1 CO8) in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.

    Journal: Nature Plants

    Article Title: Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis

    doi: 10.1038/s41477-026-02270-3

    Figure Lengend Snippet: Typical calcium signature triggered by the addition of MAMPs (150 mg ml −1 CO8) in the roots of the Arabidopsis UBQ10 :: GCaMP3 reporter line pretreated with the mechanosensitive channel blocker GsMTX4.

    Article Snippet: Experiments with the channel blockers included an additional step where LaCl 3 (10 mM; Sigma-Aldrich) or GsMTX-4 (7.5 μM; MedChemExpress) was added 15 min before treatments.

    Techniques:

    a , [Ca 2+ ] cyt levels in Col-0 AEQ protoplasts upon Srf (10 µM) or mock (WI Ca ), with or without pre-incubation with the mechanosensitive channel blocker GsMTX-4 (+Gx). n = 20 from four independent experiments. b , [Ca 2+ ] cyt response measured with the Fluo4-AM probe in Col-0 protoplasts treated with Srf (10 µM) or mock (WI Ca ), with or without pre-incubation with GsMTX-4 ( + Gx). Mean ± s.d., data are from four independent experiments with total n indicated. c , [ROS] intra accumulation in Col-0 roots 30 min after Srf (10 µM) or mock (water) treatment, in presence or absence of GsMTX-4 ( + Gx). Data are expressed as fold increase in DCFH-DA fluorescence compared to mock. Mean ± s.d., data are from three independent experiments with total n indicated. d , [Ca 2+ ] cyt signal in Col-0 AEQ protoplasts following Srf (10 µM) or mock (WI Ca ) treatment with or without pre-incubation with the calcium channel blocker LaCl 3 ( + La). Data are from four independent experiments with total n indicated. e , Calcium influx in Col-0 protoplasts measured via Fluo4-AM fluorescence after Srf (10 µM) or mock (WI Ca ) treatment, with or without LaCl 3 pre-treatment. Data are normalized fluorescence increases. Mean ± s.d., data are from at least two independent experiments with total n indicated. f , [Ca 2+ ] cyt signal in UBQ10::GCaMP3 roots treated with Srf (10 µM) or flg22 (1 µM) as MAMP, with ( + La) or without LaCl 3 pre-treatment. Signal quantified as fluorescence increase. Mean ± s.d., total n indicated. P -values from unpaired two-tailed t-test with Welch’s correction. In a and d , data show the average of luminescence (L/L max ) between 1.5 and 4 min post-treatment with Srf. Box plots show medians, quartiles, and ranges. Letters represent statistically different groups ( P < 0.05, two-way ANOVA with Bonferroni’s post-test). In b , c and e , letters indicate statistically different groups at P < 0.05, two-way ANOVA with Tukey’s post-test.

    Journal: Nature Plants

    Article Title: Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis

    doi: 10.1038/s41477-026-02270-3

    Figure Lengend Snippet: a , [Ca 2+ ] cyt levels in Col-0 AEQ protoplasts upon Srf (10 µM) or mock (WI Ca ), with or without pre-incubation with the mechanosensitive channel blocker GsMTX-4 (+Gx). n = 20 from four independent experiments. b , [Ca 2+ ] cyt response measured with the Fluo4-AM probe in Col-0 protoplasts treated with Srf (10 µM) or mock (WI Ca ), with or without pre-incubation with GsMTX-4 ( + Gx). Mean ± s.d., data are from four independent experiments with total n indicated. c , [ROS] intra accumulation in Col-0 roots 30 min after Srf (10 µM) or mock (water) treatment, in presence or absence of GsMTX-4 ( + Gx). Data are expressed as fold increase in DCFH-DA fluorescence compared to mock. Mean ± s.d., data are from three independent experiments with total n indicated. d , [Ca 2+ ] cyt signal in Col-0 AEQ protoplasts following Srf (10 µM) or mock (WI Ca ) treatment with or without pre-incubation with the calcium channel blocker LaCl 3 ( + La). Data are from four independent experiments with total n indicated. e , Calcium influx in Col-0 protoplasts measured via Fluo4-AM fluorescence after Srf (10 µM) or mock (WI Ca ) treatment, with or without LaCl 3 pre-treatment. Data are normalized fluorescence increases. Mean ± s.d., data are from at least two independent experiments with total n indicated. f , [Ca 2+ ] cyt signal in UBQ10::GCaMP3 roots treated with Srf (10 µM) or flg22 (1 µM) as MAMP, with ( + La) or without LaCl 3 pre-treatment. Signal quantified as fluorescence increase. Mean ± s.d., total n indicated. P -values from unpaired two-tailed t-test with Welch’s correction. In a and d , data show the average of luminescence (L/L max ) between 1.5 and 4 min post-treatment with Srf. Box plots show medians, quartiles, and ranges. Letters represent statistically different groups ( P < 0.05, two-way ANOVA with Bonferroni’s post-test). In b , c and e , letters indicate statistically different groups at P < 0.05, two-way ANOVA with Tukey’s post-test.

    Article Snippet: Experiments with the channel blockers included an additional step where LaCl 3 (10 mM; Sigma-Aldrich) or GsMTX-4 (7.5 μM; MedChemExpress) was added 15 min before treatments.

    Techniques: Incubation, Fluorescence, Two Tailed Test